Transforming Liver
Health

Problem

Acute Liver Failure (ALF) is a life-threatening illness with a high mortality rate of up to 50-75%. It can progress rapidly, with liver failure developing within days to weeks after the onset of symptoms, without any prior existing liver disease.

Acute-on-Chronic Liver Failure (ACLF) is a serious and life-threatening condition that occurs in people who already have chronic liver disease. It develops suddenly, often triggered by infections, alcohol use, or other stressors on the liver. ACLF can worsen quickly over days to weeks and is associated with a high risk of death, with a one-year mortality rate of around 40–50%.

Unfortunately, liver transplant surgery is currently the only available treatment, but it's expensive and constrained by limited organ availability.